specialized expertise
Exclusively
Focused on CNS
For two decades, CRC has served as a dedicated partner in neuroscience drug development, concentrating exclusively on CNS programs to better support sponsors targeting the most complex therapeutic areas. That singular commitment has shaped a model built on scientific expertise, stable teams, and long-standing relationships with experienced investigative sites.
Specializing in neurology, psychiatry, and pain drug development, our team offers sponsors the depth and continuity needed to advance programs where precision, consistency, and informed guidance are paramount.
15
FDA Approvals Supported
200+
CNS Clinical Trials Supported
81%
Positive Phase II Trial Results
(Out of 70+)
93%
Positive Phase III Trial Results
(Out of 30+)
bold CNS research
Why CNS Focus
Matters
CNS trials demand a level of precision and continuity that goes beyond traditional development. Complex, often subjective endpoints, rater-driven outcomes, and vulnerable patient populations leave little room for error. Success requires anticipating operational risk early, maintaining consistency across long timelines, and understanding how clinical and site-level decisions influence signal clarity.
Our team is built for that reality. With deep neuroscience experience, long-standing relationships with CNS investigators, and embedded assessments expertise, CRC approaches every study discipline and foresight. Our organization remains closely aligned with sites, fully engaged across the trial lifecycle, and applies structured processes that help reduce variability, ensure audit readiness, and protect signal quality. The result is consistent execution, stronger data, and greater confidence for sponsors navigating the high-stakes environment of CNS clinical development.
Neurology Trials
Supported
Neurology programs require sensitivity to subtle cognitive, motor, and functional change over time. CRC’s experience across complex neurological disorders, paired with long-standing site partnerships and consistent study teams, supports reliable detection of meaningful clinical outcomes.
Our team has supported programs across:
- Age Associated Memory Impairment
- Agitation – Dementia & Alzheimer’s
- Alzheimer’s Disease
- Amyotrophic Lateral Sclerosis
- Ataxia
- Cognition
- Epilepsy
- Multiple System Atrophy
- Parkinson’s Disease
- Sleep Disorders
Psychiatry Trials
Supported
Psychiatry studies demand disciplined oversight of clinician-rated endpoints and close collaboration with experienced sites. CRC’s psychiatric expertise and embedded assessments support consistency, reduce variability, and strengthen signal clarity across mood and psychotic disorders.
Our team has supported programs across:
- Agitation – Schizophrenia & Bipolar
- Alcohol & Substance Use Disorders
- Anxiety Disorders
- Bipolar Disorders
- Major Depressive Disorders
- Obsessive Compulsive Disorder
- Schizophrenia & Schizoaffective Disorders
- Treatment-Resistant Depression
Pain Trials
Supported
Pain trials require reliable capture and evaluation of subjective and patient-reported outcomes across varied conditions. CRC’s pain experience and established investigator relationships support consistent execution and dependable analgesic data across acute and chronic programs.
Our team has supported programs across:
- Cancer Pain
- Migraine
- Neuropathy Disorders
- Pain Modeling
- Refractory Trigeminal Neuralgia
- Rheumatoid Arthritis & Osteoarthritis
a better CRO experience
Why sponsors
choose crc
- Proven success advancing neurology, psychiatry, and pain programs from early phase through approval
- 86% employee retention supporting continuity, protocol familiarity, and consistent execution
- Embedded assessments expertise integrated with clinical, medical, and biometrics teams to protect data integrity
- Hands-on scientific and medical leadership guiding programs from IND strategy through regulatory review
- Long-standing partnerships with experienced CNS investigators and KOLs across 300+ sites for informed feasibility and durable site engagement
- Discipline, clarity, and operational rigor tailored to the demands of complex CNS programs
